Everything about Phosphatidylethanolamine totally explained
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Phosphatidylethanolamine (
cephalin) is a
lipid found in
biological membranes. It is synthesized by the addition of
CDP-
ethanolamine to
diglyceride, releasing
CMP.
S-adenosyl methionine can subsequently methylate the amine of phosphatidyl ethanolamine to yield
phosphatidyl choline.
Cephalin is a
phospholipid, which is a lipid derivative. It isn't to be confused with the molecule of the same name that's an
alkaloid constituent of
Ipecac.
Function
Cephalin is found in all living cells, although in human physiology it's found particularly in nervous tissue such as the
white matter of
brain, nerves, neural tissue, and in
spinal cord. Whereas
Lecithin is the principal phospholipid in animals, cephalin is the principal one in
bacteria. Its role in nature seems uncertain.
Chemistry
In the chemical sense, cephalin is
phosphatidyl-ethanolamine. Like Lecithin, it consists of a combination of
glycerol esterified with two
fatty acids and
phosphoric acid. Whereas the phosphate group is combined with
choline in Lecithin, it's combined with the
ethanolamine in Cephalin.
The two fatty acids may be the same, or different, and are usually in the 1,2 positions (though can be in the 1,3 positions).
Further Information
Get more info on 'Phosphatidylethanolamine'.
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